Viewing profile — nahsra

I understand this instinct, but I can see the appeal of capabilities that are well within the limits of a well-designed agentic system. Imagine asking such a system, "look at my po…

Yes, but it's held up really well in my opinion! I use this piece constantly as a reference and I don't feel it's aged. It reframed Anthropic as "the practical partner" in the deve…

Gene editing is still pretty crude in terms of delivery. Just because you can hit some germ-line cells in the liver, for example, doesn’t imply you’ll have good penetration into th…

Longevity benefits are seen at a much lower dose. https://en.m.wikipedia.org/wiki/The_dose_makes_the_poison

It won’t fly under the radar when this technology actually works. The FDA actually has warned, IIRC, that there’s a bunch of charlatans selling stuff that doesn’t work.

OP lacks imagination for sure. This would reduce infections, prevent compression lows, be more discrete and potentially increase accuracy. In no way would I describe CGM as solved,…

We made a bot, built on an [open source framework]( https://codemodder.io ), that fixes the problems Sonar (and others!) find in your code. Here are a handful of examples of pixeeb…

Grit looks cool! My apologies for the omission, I was unaware of it. I could have anchored too hard to the word "codemod" in my searches. Your tool looks awesome! > Do you have an …

This was certainly true in the past from my understanding of the history before my time. Most terms are pretty standard now. And most of them have good reasons for existing — usual…

Hi HN, I’m here to show you a new codemod library. In case you’re not familiar with the term "codemod", here’s how it was originally defined AFAICT: > Codemod is a tool/library to …

So many common, important problems (and soul-draining toil) can be resolved with codemods -- this piece (which I authored) tries to explain how and why. I am eager for feedback fro…

> Utilize Automated Tools for Code Style [...]: Ideally, comments related to code convention or commit message convention should not be necessary. These aspects should be checked a…

Yes, "discovered" was too way strong of a word there, and apologies to Charpentier. Thanks for the correction. However, she did win the Nobel prize and I have found source after so…

Jennifer Doudna [1], who helped characterize* CRISPR, worked at Yale: > Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. …

Ah, thanks! That was a proper fix.

HN added this extra slash for some reason, and I just setup a redirect on our side* to handle that weirdness. Should be good to go now!

Hi HN, I’m here to show you a new codemod library. In case you’re not familiar with the term "codemod", here’s how it was originally defined AFAICT: > Codemod is a tool/library to …

I don't have any problem getting it to help with exploit development. I never had any issue with that with any of them, in fact, which is surprising in retrospect. Inference is so …

I don't think specialized training solves any of the problems I mentioned. It doesn't increase the window size, or provide any of the types of highly specialized and optimized mult…

My experience is they're not good at this for most vulnerability classes, especially the those that are tough to discover by classical methods. Have you had any experience using th…

I said it seemed like it might be a novel addition to their practice, not to the state of the art. The question isn’t “is this possible and has anyone ever done it” - it was was “h…

The FBI took control of the botnet and re-purposed it to patch the vulnerable machines. This sounds like a novel practice addition to me? I've done some limited consulting in this …