Viewing profile — mnode

Many in the research community realised the model was wrong a long time ago. This is a great read about the reasons why: 'How not to study a disease: the story of Alzheimer’s.' by …

Base rates going up isn't fully understood but a large part is likely just changes to diagnosis. There's a recent summary of research evidence here: https://www.nature.com/articles…

A small number of readily measured physiological traits may be used clinically to evaluate therapeutics designed to slow aging and extend healthy life. Playing computer games assoc…

I use Elfeed within Emacs to browse feeds from https://hnrss.github.io/ . I have it fine tuned to be reasonably selective.

Elfeed https://github.com/skeeto/elfeed

Speedball 2: Brutal Deluxe (1991, Amiga version). Awesome, future sports sim.

Thanks for clarifying. I didn't appreciate that it only searches abstracts. That might explain some of the missing references. Anyway, great work, will look forward to using it mor…

I tried this with a question for an area I know well. It's pretty impressive but missed some key references. I'd love to see limitations like this quantified and clearly flagged. O…

Yes, that is overly cyncial. The last 10 years or so has seen big leaps in our understanding of the fundamentals of sleep mechanisms. I think there's a long way to go, but we know …

This is great! Thanks for sharing.

In this case perverse incentives. Check out 'How not to study a disease: the story of Alzheimer’s' (by Karl Herrup) for a perspective on why this is not at all surprising. That bei…

I agree, brilliant book.

Finally finished "Gödel, Escher, Bach" by by Douglas Hofstadter. Hugely original and entertaining, and although it's pretty old now, some ideas still very relevant to current AI de…

It does exist in nature and mechanisms of RNA interference are pretty well understood. The headline is actually incorrect here as the gene isn't altered, but instead the RNA produc…

Beautiful website. They massively over-claim on their science though. Their 'tech' is nothing special, people have been culturing and recording from neurons for years. And their cl…

Good reasons to be cautious, but a game changer if it works. This is gene silencing rather than gene editing so in principle risks to humans and the wider environment are relativel…

This explanation isn't consistent with my understanding. The key reasons are that SPADs have lower quantum efficiency than conventional CCDs and typical SPAD arrays have fewer pixe…