Viewing profile — mjewkes

>an awful lot of modern professional life consists of producing artifacts whose primary audience is other people producing artifacts. Slide decks for slide decks, strategy document…

Sure, they can build it here—but protectionism doesn’t deliver long-term success. In the short term, it drives up prices and makes consumers poorer. In the long run, tariffs shield…

How do you get 55%? Wikipedia says 49.8%. https://en.wikipedia.org/wiki/2024_United_States_presidentia...

CAR-T may have a ~50% cure rate for blood cancers: https://ashpublications.org/blood/article/141/19/2307/494672...

I agree completely with the first part. But SWA-1380 was a commercial operating fatality in 2018. Not a crash into terrain, but the engine definitely crashed into the fuselage.

Centrifugal forces on the spinning object will tear it apart once it goes “really fast”

The FDA approves new modalities that do things “in their own way” all of the time! Yescarta, Kymriah, the mRNA vaccines, the approved VHH, scVF and “mimetics” in the article. Here’…

>I can say this with pretty strong confidence: had the FDA not being so strict about its trials, lots of these experimental type of antibodies would have already received massived …

If you are truly netflix-to-be, you should be able to affordably incentivize your 12 key employees with equity. An exit for Employee < 50 at a netflix-to be will be in the hundreds…

Apples are better than bananas. Cherries are worse than apples. Are cherries better than bananas? -- GPT-4 - wrong gpt2-chatbot - wrong Claude 3 Opus - correct

Notably, if you ask it to transform the statements to formal logic, you get a correct response! This stuff is truly magic. https://chat.openai.com/share/81e45fef-a72b-4258-98d6-5c8…

For sure. It's not a fair prompt at all. I'm super bullish on LLMs and am using GPT-4 in production right now. This stuff is magic. It's actually hard to find short, simple, "plain…

My current favorite “LLM breaker” below. GPT4, Claude, and this all fail. —- Apples are better than bananas. Cherries are worse than apples. Are cherries better than bananas?

Editorial write-up: https://archive.ph/0T2XI

Worth checking out the talk page. Looks like this whole article is out of date and that much of the problem is resolved.

This seems credible: https://ascopubs.org/doi/full/10.1200/EDBK_288015

As fabiancook mentions, credible sources all end up on pubmed within a year or two of publication, so it's an excellent resource. That said, Pubmed is an aggregator, not a curator.…

https://www.rand.org/pubs/research_briefs/RB9412.html and The Great American Drug Deal, by Peter Kolchinsky. Specific claims: - The US pays more for new drugs than the rest of the …

No assumptions. The rand article addresses that directly.

Hey biorach - I would suggest: https://www.rand.org/pubs/research_briefs/RB9412.html and The Great American Drug Deal, by Peter Kolchinsky. Specific claims: - The US pays more for …

The claim is largely true for drug development, but not for routine procedures. Those are expensive for unrelated, and largely pathological, reasons. I would suggest: https://www.r…

The claim is largely true for drug development, but not for routine procedures. Those are expensive for unrelated, and largely pathological, reasons.