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Viewing profile — mcbain

mcbain

HN member
Joined
Tue, Sep 21, 2010, 1:53 AM UTC
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1,021
Public activity
203 items

About mcbain

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Recent public activity

  1. comment
    Comment #47492446

    You might enjoy the matrix of regional sizes and names on Wikipedia: https://en.wikipedia.org/wiki/Beer_in_Australia#Beer_glasses No, us locals don't know them all either!

  2. comment
    Comment #47486713

    https://www.avherald.com/h?article=536bb98e > Captain and first officer are reported to have died in the accident, two fire fighters on board of the truck received serious injuries…

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  5. comment
    Comment #47029356

    The former. It doesn't quite roll off the tongue, but with my (Australian) accent the difference is minor.

  6. comment
    Comment #47021217

    Yes, with MRI brain too. I was on 4/year, but that number is reducing as time goes on without recurrence.

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    Comment #47018946

    I have multiple scans a year. "Scanxiety" is real.

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    Comment #47018938

    Spot on. And dealing with false positives sucks. One caveat is that regular PET isn't so good in the brain - there is so much metabolic activity that everything glows. So I get an …

  9. comment
    Comment #46358875

    Previously: https://news.ycombinator.com/item?id=45514378

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    Comment #46042504

    Linde was definitely around as a distinct brand in Australia before they bought BOC in 2006, but since then as you said, they now just trade as BOC.

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    Comment #45641201

    When have they ever claimed that?

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    Comment #45191636

    As others pointed out, these are stage I trials and these are patients that have had other treatments already. In particular the melanoma patients had already had other immunothera…

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    Comment #45145894

    The testing here is not just that it is safe on skin, but the SPF test itself is done by slathering it on humans and exposing them to light to determine a rating.

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    Comment #44318166

    Also the club scenes, with a bunch of regulars from Hellfire/Black Market, on Regent St. (Now a cafe supply store.)

  15. comment
    Comment #44244216

    Sadly Richard has now had recurrence. There is still hope for this treatment for others, and it likely extended his life, but it isn't happily ever after this time.

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    Comment #43204707

    https://www.nature.com/articles/s41591-025-03512-1 Ipi/nivo/relatlimab and then a peptide vaccine that they haven't written up yet.

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    Comment #43204656

    No chemo. The entire idea of this regime is to hit the tumour with immuno to get the reaction. They want lots of tumour cells and for it to be "treatment naive" - Richard hadn't ev…

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    Comment #41377469

    https://youtu.be/Y5K9HBiJpuk I think Petter's (Mentour Pilot) delve into it is quite good - there's a lot of detail I hadn't known.

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    Comment #41333849

    It's easy for (say) AWS to terminate your EC2 instances. Do they also delete your DB backups? Delete your S3 buckets? All of these incur costs. How hard a cap do you want?

  21. comment
    Comment #40973947

    One big trial still going: https://clinicaltrials.gov/study/NCT03739931

  22. comment
    Comment #40973910

    There's a bunch of different immuno types for melanoma (and other cancers). That one is a combo of nivolumab (aka Opdivo) and relatlimab. Nivo is used a lot for melanoma, also comm…

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    Comment #40463637

    It does launch an instance and take a snapshot but what's happening is the sysprep and OOBE stuff that can take 10 mins or so (you can find it in the console and startup logs). Tha…

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    Comment #40168173

    This is seeing great results but unless I'm mistaken, this started stage III in July 2023: https://classic.clinicaltrials.gov/ct2/show/NCT05933577