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You might be interested in reading about "chaperone proteins"!

A single flow cell contains a few thousand pores (I think this is what you mean by "holes") that are all at different stages of passing different molecules, with signal data being …

I used to run a department at a biotech where ~50% of our data came from MinIONs (although, that said, I'm a bioinformatician, rather than a molecular biologist), so I can answer y…

This is a common, and often justified, though not always fair, criticism. MinIONs have an error rate of around 10% for _any given base_. Moreover, these errors aren't entirely inde…

It's a complicated issue; I tend to think of the error component of any one MinION observation as being a function of the k-mer in the pore at the time (i.e. the subject of the obs…

As others have said, you're reading a sliding window of k-mers over the target sequence; I think for the MinION k is presently 5. To answer your question directly, it struggles wit…