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mansr

HN member
Joined
Thu, Sep 17, 2009, 3:23 PM UTC
HN karma
619
Public activity
266 items

About mansr

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Recent public activity

  1. comment
    Comment #30065288

    I stopped reading at the part where he spends a full page on semantic games around the precise meaning of the word vaccine, misspelling the name of a famous dictionary in the proce…

  2. comment
    Comment #29591813

    A quick web search suggests that it's nothing to be concerned about. https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa...

  3. comment
    Comment #25123961

    It's the standard method, and I see nothing wrong with it. What you suggest (deliberate exposure) is called a challenge trial. This is normally considered ethical only when an effe…

  4. comment
    Comment #25123813

    Nothing is misleading. Half the participants got the vaccine, the rest placebo, before going about their usual lives. Now, a few months later, 95 cases have been confirmed across b…

  5. comment
    Comment #25122093

    In the Pfizer trial, all the subjects in the interim evaluation had symptomatic infection confirmed by PCR test. I'm not sure about Moderna, but it's likely to use the same or simi…

  6. comment
    Comment #25122023

    One factor speeding up the phase 3 trials is the high rate of infections. Since the evaluation is done at a set number of confirmed cases among the test subjects, this happens much…

  7. comment
    Comment #25115552

    The largest percentage increase may have been in that age group, but since the base rate is very low, it still amounts to few deaths overall.

  8. comment
    Comment #25113259

    According to the Guardian, AstraZeneca is looking at charging £3 per dose for their vaccine, assuming it gets approval. https://www.theguardian.com/world/2020/nov/16/moderna-covid-…

  9. comment
    Comment #25112719

    This isn't the final evaluation. There will be another at ~150 cases. The numbers may seem small, but this is enough for the purpose of deciding for or against approval. Anything o…

  10. comment
    Comment #25112510

    I happened to read it here recently: https://www.theatlantic.com/magazine/archive/1957/02/how-goo... No, that's not a scholarly article.

  11. comment
    Comment #25112330

    Both groups have (approximately) the same size, in the tens of thousands. The first evaluation is done when 90 or so cases have been confirmed, not knowing which group they belong …

  12. comment
    Comment #25112093

    Verifying the expected immune response (antibodies) is (part of) phases 1 and 2, if I've understood things correctly.

  13. comment
    Comment #25112037

    Early polio vaccines did.

  14. comment
    Comment #24475935

    Following that method will make you a Scientologist, not an expert.

  15. comment
    Comment #24472411

    Niels Bohr, widely regarded as an expert, has said that an expert is someone who has made all the mistakes which can be made, in a narrow field. If you want to become an expert, yo…

  16. comment
    Comment #23804481

    The problem addressed by git or any other serious version control system is complex. Any seemingly simple solution will be severely limited, even if it does some particular things …

  17. comment
    Comment #23804203

    People who criticise git fall into two categories: - Those who have never used Clearcase, Perforce, or any other enterprise monstrosity. - Those who have and suffer from Stockholm …

  18. comment
    Comment #23500814

    > just... why? It's called "virtue signalling," I'm told.

  19. comment
    Comment #23205685

    "Hopefully some place I didn't anticipate."

  20. comment
    Comment #19797056

    They switched from a T-rex to a hat. Makes sense.

  21. comment
    Comment #19289964

    Yes, they do.

  22. comment
    Comment #17714727

    > Why do keyboards have hard-wired cables anyhow? Low-speed USB devices are not permitted by the spec to have a detachable cable. The fancier keyboards are probably full- or high-s…

  23. comment
    Comment #16151261

    Well done to all of you for cultivating these puns.

  24. comment
    Comment #15428724

    His Permutation City is also good.

  25. comment
    Comment #13168110

    What I said about inline is true of C99. C++ might be different though. It is also true that Unix linkers give an error if the final set of object files to link contain more than o…