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joshuamcginnis

HN member
Joined
Fri, Nov 14, 2014, 8:29 PM UTC
HN karma
1,239
Public activity
336 items

About joshuamcginnis

Biologist and software engineer.

Researching fungal natural products and the use of generative AI in biotech.

josh at everymanbio.com

Recent public activity

  1. comment
    Comment #49161936

    > If squeezing the best open models onto GPUs and serving them to millions of developers sounds like your kind of problem, come work with us. What is the typical job title and/or s…

  2. comment
    Comment #49028941

    I like https://www.dynadot.com/ . Good prices and privately owned for 30+ years.

  3. comment
  4. comment
    Comment #48702584

    I'm just sharing my personal preference and not trying to tell people how to live their lives. I don't like personally like the idea that I'll only be healthy if I take this drug f…

  5. comment
    Comment #48702564

    I think there's a distinct difference between taking medicine for things you can fix on your own (diet + exercise) vs things you cannot (excess acid production).

  6. comment
    Comment #48702471

    Studies show almost all subjects regained the weight and reversed gains within 2 years. This means underlying issues (e.g., food addiction) aren't being addressed. Short of changin…

  7. comment
    Comment #48667690

    How the information is shared can be as important as the act of sharing it in the first place. You might have a particular voice and style for communicating these ideas, but your a…

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  9. comment
    Comment #48429111

    I wonder if any of this was used to produce Backrooms

  10. comment
    Comment #48405476

    Massive productivity gains.

  11. comment
    Comment #47681626

    As someone with a massive collection of antique postmarked postcards (probably the largest in the world for a particular city), this is very helpful and encouraging for getting my …

  12. comment
    Comment #47302172

    I'm truly sorry to hear about your suffering. Have you considered giving your life to Jesus? It can be a great source of healing and comfort in your time of need. I'd be happy to t…

  13. comment
    Comment #47255995

    I culture fungus, perform DNA extraction, run PCR (polymerase chain reaction - the process used to clone the gene(s) I want to sequence), and gel electrophoresis in my home lab. I …

  14. comment
    Comment #47169204

    This sucks because I just set everything up at OVH this month. Who else should I be looking at with better pricing? (or least, better resources for the price)

  15. comment
    Comment #47090561

    Also, git's "master" branch is named after a master recording or master copy, the canonical original from which duplicates are made. There is literally no reason for it be offensiv…

  16. comment
    Comment #46967860

    My views on market validation have changed with age. What I've observed after talking to hundreds of founders is that it's now so easy for someone to enter a market that it seems l…

  17. comment
    Comment #46967811

    Yea. Perhaps a better metric to use would be Seller's Discretionary Earnings (SDE) which includes the owner's salary, benefits, and discretionary expenses, after adjusting for non-…

  18. comment
    Comment #46889516

    > In short, occupywallst.org is a living archive and occasional update point for a landmark left-wing protest movement that put economic inequality and corporate power at the cente…

  19. comment
    Comment #46889422

    I did a little (very little, I asked an LLM) what it would cost to produce this report in today's dollars. The answer came in as roughly $90,000–$180,000. Worth it or accurate? I d…

  20. comment
    Comment #46802662

    If you're into this and you're ever in Bozeman Montana, check out the American Computer and Robotics Museum. It's excellent! https://acrmuseum.org/

  21. comment
    Comment #46790693

    Exactly. UV would definitely work but is also destructive to many kinds of items.

  22. comment
    Comment #46789670

    I've isolated many xerophilic molds, mostly from caves around the US. As the article stated, the most you can do is spray ethanol on the article and wipe it down. That'll kill most…

  23. comment
    Comment #46714835

    My original argument is getting dismissed, in part, because people are fearful of how it would be implemented while at the same time, completely hand-waving over the obvious flaws …

  24. comment
    Comment #46714769

    It's a clear sunny day and you ask me, "is it raining?". I answer, "it's not snowing." Am I lying?

  25. comment
    Comment #46714736

    It's a good starting point because the commandments were given by God. And without God, there is no objective moral standard. Everything, including your opinion on my point of view…