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Viewing profile — jashephe

jashephe

HN member
Joined
Mon, Sep 02, 2013, 8:24 PM UTC
HN karma
197
Public activity
38 items

About jashephe

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Recent public activity

  1. comment
    Comment #47311870

    It sounds like you want a dictation mic. Philips’s SpeechMike and OM System’s (formerly Olympus) RecMic are big in the healthcare space. My SpeechMike is wireless with a USB dongle…

  2. comment
    Comment #43475015

    The periodic table poster under "High binding problems" is billed as evidence of model limitations, but I wonder if it just suggests that 4o is a fan of "Look Around You".

  3. comment
    Comment #39709614

    I'm a little disappointed that their linked preprint doesn't appear to include any molecular biology; i.e. they don't actually try to synthesize any of their predicted sequences an…

  4. comment
    Comment #35937425

    A tangent: does anyone have recommendations for a library for easy Swift-Rust interop? This is a cool tool, but I’d much rather make a GUI natively with e.g. SwiftUI and then call …

  5. comment
    Comment #33615833

    All sorts of offtopic prompts are unsurprisingly generating nonsensical answers, but even prompting with "lecture notes on clathrin-mediated endocytosis" yielded: "In the case of c…

  6. comment
    Comment #30891286

    Global models of gene expression for an entire cell are fairly distant at this point, but there is quite a bit of work into modeling transcriptional activity from sequence. If you'…

  7. comment
    Comment #28314106

    I'm confused. Where does this say the vaccine is mRNA? The Valneva VLA15 website explicitly states "VLA15 is a multivalent recombinant protein vaccine" [1], and the linked press re…

  8. comment
    Comment #27612325

    Not sure why a direct quote from the article is getting so heavily downvoted. Maybe there’s something here, but if the variants were in the published paper, it doesn’t really matte…

  9. comment
    Comment #27586461

    Taum Sauk is unusual in that the dam fully surrounds the upper reservoir (i.e. the lake was made from scratch), although certainly all types of dam can fail.

  10. comment
    Comment #27296284

    I'd be quite interested to see if there's any correlation between Valisure's measurements and time elapsed since manufacture for each lot.

  11. comment
    Comment #26403090

    Isn't pumped storage hydro kind of that "silver bullet"? At least in places with the right geography?

  12. comment
    Comment #25187281

    Indeed. Maybe someone with more expertise can chime in — it's not clear to me if getting a vaccine with the chimp adenovirus backbone would preclude the possibility of getting anot…

  13. comment
    Comment #25034732

    Based on this NYT article [1], some logistics companies planning to store and transport the vaccine are using freezers from Stirling Ultracold. It may just be a curiosity, but thei…

  14. comment
    Comment #24787829

    It’s always surprising to me to see an article like this that’s vaguely about a person, without seemingly any attempts to reach that person for comment. I’ve filed issued on a few …

  15. comment
    Comment #24708095

    While "Heroes of CRISPR" is a fairly detailed history of the whole affair, it's always worth noting that it was written by Eric Lander, the director of an institute with a strong v…

  16. comment
    Comment #24315984

    Indeed. In Chadwick Boseman’s case, the onset was at _such_ a young age that it suggests (total speculation) he might have had a hereditary cancer syndrome or some other familial r…

  17. comment
    Comment #24244126

    Just to clarify — the vaccine uses as its backbone a type of adenovirus that typically infects chimpanzees, modified by the addition of pieces from SARS-CoV-2, but the experiments …

  18. comment
    Comment #24067695

    The above is a good example of how results can be "wrong" in theory papers, but I work in an experimental field of research and at least in my world, having a paper present results…

  19. comment
    Comment #22733285

    This calls to mind the ever-relevant “Science: The Endless Frontier” [1] by Vannevar Bush, who more or less oversaw the entire American federal research enterprise during and post-…

  20. comment
    Comment #22177006

    Oh, absolutely. I guess I was wondering if accusations alone would serve to substantially inconvenience or embitter individual scientists, or decrease public trust in academic rese…

  21. comment
    Comment #22176934

    The conspiracy theorist in me can't help but wonder if "leaking" forged documents of this nature could be an effective way for China or another foreign government to sabotage the l…

  22. story
  23. comment
    Comment #19964794

    Some folks have raised plenty of practical/medicolegal reasons, but it's also worth noting that patients are often not comfortable being told that they have an "anomaly" that their…

  24. comment
    Comment #19964743

    Some of the comments here don't touch on the practical limitations of this, but here's one — I'm at a 1400+ bed top-10 US academic medical center, and even our outpatient MRI machi…

  25. comment
    Comment #19667537

    (for context) https://twitter.com/realDonaldTrump/status/11178449872934871...