Viewing profile — iso1337

A lot of jobs are at SMEs but they’re low quality service jobs… Your local restaurant with thin margins and underpaid staff is an SME

Q1 - How much effort did you put into deterministic guardrails like AST linters, etc? I find there’s a ton of slop unless hard guardrails are added, eg step 1 is just around syntax…

IIUC its just strict separation of concerns Eg UI cannot reach down and directly read config files Configs must be only read by (im assuming) a storage interface layer called repo …

NIH should build more institutes in cheaper areas (eg not NoVa). It’s a win win since it will help revitalize poorer areas of America and save on costs. It will also tilt more sena…

And that's why a ton of video lectures from UC Berkeley had to be taken down due to lack of captions. https://news.ycombinator.com/item?id=13768856 The spirit of the law is good, b…

Any publicity is good publicity. Sprinkle in some words about "this needs further study" and hope someone comes along to fund the next few years of your lab.

Their claims around Type IIS assembly are also suspect. eg in Golden Gate assembly, you choose Type IIS that reach over and cut, so the restriction site is absent from the final as…

There is a huge variety of viruses, just because someone wrote the equivalent of "Hello World" doesn't mean you can write a complicated CMS anytime soon. Synthetic biology (the act…

https://dandelionenergy.com/ is one company trying to scale this. In general, Americans don't want to pay a huge cost upfront for some efficiency gains. Especially since traditiona…

LFP batteries are the future for home energy storage. Less fire risk, cheaper. They're heavier, but that's totally fine for a stationary application. Does GM have any competency in…

The fact that white is the default is already problematic.

I think so many of these issues can be solved by going on road diets and dedicating an entire car lane to bikes. Use the carrot and the stick to incentivize a healthier mode of tra…

I don’t know if you have relatives or children with Down’s, but it is no walk in the park. Forcing parents to have disabled kids is not good policy either.

Instagram is one of the few platforms that allows you to comment on ads. It's pretty interesting as the comments tend to be overwhelmingly negative.

You want an unregulated market like Texas?

There’s no network effect though? On FB, more people on the social network means the draw to the n+1st user is immense. Whereas for home batteries, it could be the inverse. As more…

I think you’re conflating the UI of Amazon with the more difficult problem of getting a large distributed system to work at scale. Conversely, if your ECU has minor glitches, will …

The local HK government has no power, it is controlled by the CCP. So at least in this case, I can buy the argument. An American analogy of your argument would be something like “b…

says the study’s senior author, Xuanhe Zhao, professor of mechanical engineering and civil and environmental engineering at MIT. The study also includes lead authors Chonghe Wang a…

https://en.m.wikipedia.org/wiki/Plasma_deep_drilling_technol... Plasma drilling sounds like it could be useful - the plasma essentially melts the material surrounding the borehole …

https://acoup.blog/tag/lord-of-the-rings/ https://acoup.blog/2019/07/12/collections-the-lonely-city-pa... Great high quality blog from a historian analyzing the logistics of LOTR a…

This is covid misinformation. It's always dangerous to extrapolate the results of a study like this to what it means for the vaccine. For a decent discussion: https://www.reddit.co…

Americans love to come up with complicate theories about why it’s impossible for them to lose weight. Go to Europe or East Asia and you’ll see it’s definitely possible and definite…

“Wokeness” treats Asians as white adjacent and often dismisses the real issues they face because of an idea that other people suffer more. Eg see efforts to use BIPOC instead of PO…

It's the 3' (3-prime) UTR (un-translated region). It can affect the translation of the mRNA. https://en.wikipedia.org/wiki/Three_prime_untranslated_regio... . The next thing is the…