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And also their electricity bills rising because of datacenter power demands.

The Smith chart is the electrical engineer's favorite: https://en.wikipedia.org/wiki/Smith_chart You either love it or hate it, depending on how well your electromagnetics class wa…

Unpaywalled: https://archive.is/dmp0m

The cynical part of me wonders: if this has been a promising approach for 10+ years, why weren't they able to secure VC funding years ago (or nonprofit biomedical research funding …

Thanks for the response! This is very cool and sounds like a reasonable plan. Best of luck!

I am totally onboard with the premise (as a TechBio-adjacent person), and some of the approaches you're taking (focused domain-specific models like Orthrus, rather than massive fou…

There are biotech companies like Eikon Therapeutics ( https://www.eikontx.com/ ) where super-resolution microscopy in living cells is a central part of the platform. There is also …

A thread from yesterday about why gene therapy hasn't reached its potential: https://news.ycombinator.com/item?id=44573193

DeepMind/Google does a lot more than the other places that most HN readers would think about first (Amazon, Meta, etc). But there is a lot of excellent work with equal ambition and…

Very cool. There are also methods that allow you to extract some notion of motion from variability in CryoEM data, e.g. CryoDRGN-ET [1]. I'm curious if you've worked with any of th…

thought this was about tracing neural circuits in the brain and was disappointed.

Detailed New England Journal of Medicine article about this case: https://www.nejm.org/doi/full/10.1056/NEJMoa2504747 And an Editorial piece (more technical than the NYT): https://…

It is possible that they are licensing technology that was developed in academic science and are raising money to scale it up and get it ultra-standarized for commercial scale. I a…

Indeed, now is the moment to step on the gas in biotech. The past 15 years have been nothing short of extraordinary in the field. We finally have the tools needed to effectively me…

It is worth mentioning that China is heavily investing in biotechnology and they are getting genuinely good at the more commodified parts of the industry. This blog post [1] is lon…

Lots of biotech companies are working on immunosuppressant-free islet-equivalent transplantation. Two examples off the top of my head: Sana recently announced islet cell transplant…

1) Creative projects beget creative projects. When you start working on one project, you'll have ideas for a dozen more, and probably one of those might actually be a good project …

I am pretty sure that the CGP Grey video was the core inspiration for this article. Nearly every image in the article was featured in the YouTube video, which predates the article …

Have you looked into Nebula Genomics? They will do 30X coverage WGS for $299, and will give you the underlying data so you can analyze it on your own (in addition to their analyses…

Nebula Genomics: https://nebula.org/whole-genome-sequencing/

I would recommend the edX Introduction to Biology course [0]. It is a simplified version of the introductory biology course at MIT, that doesn't _focus_ on naming/defining things i…

The Vital Question, by Nick Lane is a pretty good book that takes a thermodynamics first approach to this question.

Mostly agreed. In my eyes, the takeaway from this piece is not that neuroscience is futile and that we should give up, but rather that we now should redouble efforts on analysis me…

The stories in this piece really highlight the importance of having these tough conversations with family members about what you want to happen for your own medical care if the wor…

On the topic of describing the events of the code (cardiopulmonary resuscitation) in great detail, there have been studies showing that bringing the family into the room during a c…