Viewing profile — elamje

I’m always excited when Cloudflare starts offering things that I had to use other providers for because I know it will be solid. We used Statsig at Function. It started out as 2 of…

> Not only does this obviously not result in lower US prices Maybe in Pfizer’s portfolio this is true. However, I just watched the Amazon Pharmacy pricing for GLP-1s drop substanti…

Not arguing on broken internal pricing dynamics that are skewed by all sorts of gov programs and payors. It’s about external, global pricing dynamics. The site clearly isn’t going …

Can you explain from first principles how the US market gaining MFN pricing does not benefit Americans? Open to changing my mind

The situation is basically this - Novo and Lilly spent billions making Semaglutide, Tirzepatide, and future formulations/modalities. They are going to monetize this heavily while t…

Where did you hear this?

I was talking to someone about this the other day. I was part of a team at NASA that developed a cooling system for the ISS and this whole premise makes no sense to me. 1. Getting …

this hides major dilution until future financings best to treat it like an expense from the perspective of shareholders

think about how to start and maintain a better founder dynamic for the next company more than trying to course correct what you already have

you’ll be happier on the morning after you leave than you even remembered was possible

Have a friend high up at one of the “Big 3” in this space. The entire business model is predicated on injecting themselves as the last click for attribution even when they weren’t …

The closest software analogy I’ve heard is like passing around a callable/function with a standard interface. An LLM can call the callable and work with the returned data without n…

Do you think SpaceX or similar would be attacking this problem space if there was a business to be had here? Seems like a fun pet project that will lose money indefinitely, but lov…

100%

Nearly 10 years ago, I was at a Spotify recruiting event and they told us how they did embeddings at the time. They took all user generated playlists and projected the songs into v…

$1,000/mo in a low income area of Dallas is a lot of money. Going from a $700/mo to a $1,700/mo apartment in Dallas is luxury. Not sure you're seeing this one clearly....

Massively changed my life trajectory. I was working on my first "startup" (if you want to call it that) and wasn't getting traction. The owner of a software consulting firm found m…

Most people don’t know that there are species that can, e.g. drop their metabolic rate down to .01% of baseline to survive without water or food for 30 yrs. Or survive in high radi…

Should have maintained a python interoperable runtime. Less and less people use JVM languages for things like web apps, data eng, data science, ML, etc.

This is awesome. I am highly interested in the BioTech space and happened to work with electro-wetting for zero gravity space applications almost 10 years ago! This is such a cool …

I run a bunch of blogs from a single Django app with a CMS, SQLite, and extremely optimized SEO hacks. It’s the perfect use case, light on writes, super heavy on reads. Almost as f…

Growth hacking, marketing, and sales for SMBs and solo-preneurs. Think highly paid freelancers (we find opportunities for them) and blue-collar service companies (they want more le…

I worked on this in 2018/19. It's a really hard problem, and the only people I've found doing it at scale is a small Norwegian company called https://piql.no . They encode large fi…