Viewing profile — ebolyen

I recall SimTower had bomb threats for the security team to deal with.

QIIME 2 creates scientific visualizations as single-file web apps, we've been using this pattern since late 2016 with a great deal of success. Example gallery: https://view.qiime2.…

Was it this exp-minus-log arxiv paper?: https://arxiv.org/html/2603.21852v2

I think people are reacting to the press-release more than the work. I don't see why this is definitely doomed just because they discuss beta-amyloid plaques. Those exist and are r…

Very relevant comic: https://thejenkinscomic.wordpress.com/2024/12/01/brady-bunch...

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I'm not aware of any, but it wouldn't be insane to build a seekable deflate implementation by defining offsets in a zip comment. This would leave the zip file backwards compatible …

Seems we need a .zipkeep file then. Just kidding, I don't see how the overhead of the directory entry is even remotely enough to warrant removal. Most of the magic can be left to e…

There's really a lot more you can look at here. Lot's a prior art on super-cookies and fingerprinting: https://coveryourtracks.eff.org/ https://amiunique.org/

The moxy of this is inspiring. I'm curious to know what you would rate as the most important features to make this work? It seems like calc+if do a lot of the heavy lifting, but th…

It does seem like the state of the art differs from popular understanding. Not only is mitochondrial DNA straight forward (although not especially useful for forensics as it is mat…

It is the initial purpose of a microbiome to be at least commensal, in that it is usually prohibitively expensive to maintain a sterile environment so the odds of a true pathogen c…

No, because alignment, in the general case, is O(n^2). It is ironically one of the more tractable and well solved problems in bioinformatics.

If anyone is interested in a more formal descriptions of these control-loops, with more testable mechanisms, check out the concept of reward-taxis. Here are two neat papers that I …

Not an expert, but I have a bit of formal training on Bayesian stuff which handles similar problems. Usually Gibbs is used when there's no directly straight-forward gradient (or wh…

It's been a long time since I took a class like this, but I definitely had a similar experience to the author. Ideas like fold and map where _never_ mentioned in lisp (to exaggerat…

> I wish you luck with tracking down versions of software used when you're writing papers... especially if you're using multiple conda environments. How would you do this otherwise…

This is true of corals, and they are often considered "colonial" organisms instead of an individual. That said, I don't think anyone who studies biology is particularly concerned w…

I see, so it's a procedural language that is well understood by those who fly (not just some semi-structured data or ontology). This is a great example of the advantage of domain e…

I like that approach.

I don't know, that sounds like a complex kind of ingest which could be arbitrarily subtle and diverge over time for legal and bureaucratic reasons. I would kind of appreciate havin…

Branding works on primitive types as well, which is I think the most interesting use case. I would also agree that it's harder to confuse complex types as any single instance of a …

Slightly tangential, but is there any hope of seeing Polar return as a (maintained) open source system? I absolutely love the concept of using a logic language for authorization, a…

> You don't want negative numbers because that would require the description of a category to change based on whether it is positive or negative That's actually already how it work…

I see a lot of consternation about credits and debits and the nomenclature. Something that makes this simpler to think about from a modern perspective is that accounting is older t…