Viewing profile — dpatrick86

It would be really interesting if cars did this by default. Maybe it could figure out your threshold, how much of an outlier you are, and then you could opt-in to a new threshold t…

Artificial is fine and playing word games for pedants is a trap.

Getting big "on a bender" vibes from Elon right now...

Some use cas9, such as dead cas9 (has endonuclease activity removed), and others do not. Great interview where Dr. George Church talks base editing and CRISPR: https://www.foundmyf…

This is being reported as false https://ew.com/music/jerry-lee-lewis-alive-after-erronerous-...

At least in the case of the heart, there’s the beginnings of evidence that is suggestive of the fact that the damage is not simply incidental to systemic inflammation. https://medi…

Your point may be broadly true but subject to important caveats. Cancer is a very heterogeneous disease. There is evidence that _some_ cancers can use, for example, acetoacetate. h…

Wow, refreshing. To me, the most interesting part here is the incentive. It sounds like they ultimately just wanted to rise to the standard once it was made exhaustively clear. The…

Might be inhibiting sirtuin activity... http://www.jbc.org/content/277/47/45099.short

What makes you think NMN has been "proven to be safe?" That's a pretty strong standard to conform to. There's virtually no clinical work that's been done at all, for starters. A lo…

Taken in light of the existence of the glymphatic system, a robust mechanism of clearance activated by slow wave sleep, what is more likely... misfolded protein accumulation is inc…

Allele misassignment is another rampant issue. https://www.ncbi.nlm.nih.gov/pubmed/18154681?dopt=Abstract

I appreciate your comment, despite not relating to it very well and it seeming a bit strange to me. I know that might come across a bit odd, but it's refreshing to actually try to …

It sure seems like patterns of cortical activation (or something like that) could be compared to some sort of waking standard to take a very good measured guess at some point.

That's awfully late in life to be developing a foundation for morality. It seems far more likely to be extremely influenced by early upbringing. More controversially, there may eve…

Interestingly, the legacy of Biosphere 2 includes the recently emerging fasting and fasting-mimicking science demonstrating some interesting healthspan promoting properties. Dr. Ro…

This was based on the SELECT trial data, which means that it could just as easily be measuring the effects of a very large and prolonged dose of 400 IU of alpha-tocopherol as it is…

What if it's both?

VSL#3 is one that has a lot of clinical research (search Google Scholar or PubMed). The catch is that the company producing VSL#3 no longer uses the formula that historically was u…

Some research is adopting this pattern too. A great example is Dr. Satchin Panda's clinical trial on time-restricted eating. You self-select an eating window and then document it t…

Not required for the optional smart key system.

It might be written better as, "Cardiometabolic resilience may be neurobiological." Of course, mental resilience being neurobiological would be a banality, however, they are talkin…

Following the instructions pedantically (e.g. emphasizing "uniquely identify," especially for the individuals) probably leads to an enormous biasing of the score.

Interesting journalistic experiment, however, ads like these are irrelevant unless they can push the amount of exposure that shifts elections. That's going to take a lot of money. …

On the contrary, Bredesen talks about viruses quite a bit in this recent interview... https://www.youtube.com/watch?v=Sq7uVZ_0D3U Specific time points listed in the show notes... h…