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daemonk

HN member
Joined
Fri, May 03, 2013, 12:17 PM UTC
HN karma
1,263
Public activity
417 items

About daemonk

Entrepreneur, founder, bioinformatician, data scientist

Recent public activity

  1. comment
    Comment #48142066

    I am getting the exact opposite experience. But it is probably because I am in a domain where code/software is a tool, not the product. I find myself learning exponentially faster …

  2. comment
    Comment #48110106

    I don't disagree with Bambu from an operational standpoint, but disagree with their handling of this. They are offering a cloud infrastructure that allows users to remote control t…

  3. comment
    Comment #47607345

    I have a data science/engineering background. From my perspective, using AI is like mining the solution space for optimality. The solution space is the combinatorics of the billion…

  4. comment
    Comment #47507790

    I AI coded an entire platform for my work. It works great for me. I also recognize that this is not something I want to make into a commercial product because it was so easy that t…

  5. comment
    Comment #47378955

    Yeah this is the simpler and also effective strategy. A lot of people are building sophisticated AST RAG models. But you really just need to ask Claude to generally build a semanti…

  6. comment
    Comment #47221218

    Just write a Claude OS already.

  7. comment
    Comment #47213312

    I did this in the beginning and realized I never went back to it. I think we have to learn to embrace the chaos. We can try to place a couple of anchors in the search space by havi…

  8. comment
    Comment #47208101

    Were there any discussion from either company about giving government access to consumer data from the the consumer product?

  9. comment
    Comment #47208024

    It's a different skillset and way of thinking. Engineers tend to think vertically deep on technical problems. With AI, you have to think horizontally broad and vertically up on the…

  10. comment
    Comment #46916755

    Pretty cool technique using complementary overhangs and toehold sequences to generate a 3-way heteroduplex, ligate knick, and then remove barcode duplex. They don't give much detai…

  11. comment
    Comment #46618808

    I am unsure of the impact of this to the regular consumer as this seems like a pretty niche area. But it's kinda shitty that interpersonal relationships of two companies are impact…

  12. comment
    Comment #45529460

    It reeks a bit of tech self importance. From an overall business context, you balance time/effort vs short/long term reward and design or fix things when you need to. There are man…

  13. comment
    Comment #45304018

    So the queen can lay 3 types: hybrid female, Ibiricus male, structor male. Did they do karyotyping? Is it actually that the queen somehow removed its own genetic material from the …

  14. comment
    Comment #44677866

    The haplotype phasing strategy is the key method here. The phasing method is described in a previous paper: https://www.nature.com/articles/s10038-022-01049-6

  15. comment
    Comment #44649574

    I think this sentiment has probably been echoed through the ages. It feels like there's an assumption that we've reached some kind of a complexity ceiling and compressing complexit…

  16. comment
    Comment #44495297

    It might not be the mainstream on HN, but most popular polls I've seen show similar trends of a lesser proportion of people wanting to live longer, citing the same societal collaps…

  17. comment
    Comment #44493184

    This isn't an unpopular opinion. I would argue this is the mainstream argument. I think all medical advances benefit the wealthy first and then becomes more affordable over time. T…

  18. comment
    Comment #44074610

    At a higher level, MCP seems wants to enforce a standard where no standard exists. I get that the low level technical implementation allows AI to utilize these tools. But there doe…

  19. comment
    Comment #44054128

    Learning biology is a great insight to how humans think about complex systems. We tend to utilize a reductionist and engineering approach to figure out how things work. This is a p…

  20. comment
    Comment #43767709

    I don’t think we are going to agree on this. At the end of the day we are really just disagreeing on how seriously we should take AI-ification of software engineering. I take a lig…

  21. comment
    Comment #43766754

    Sure. But it's not really about you. I wouldn't break into someone's house and tell them they painted their house an uninformed color. If something sucks or won't scale, it will so…

  22. comment
    Comment #43764500

    [flagged]

  23. comment
    Comment #43003936

    I think this is just subject to normal market forces and very product dependent? If you have engineering skills that are not easily found, then you can ask for more. If the founder…

  24. comment
    Comment #42428793

    TXTL systems already works. And there are antibodies (not many) that can only be produced cell free. The problem is really scale.

  25. comment
    Comment #42424975

    Cell-free synthesis is the next step. Theres slow progress, but very interesting operational models if it works.