Viewing profile — couteiral

Yes: they predict structures using MSAs, without alignments to known protein structures in a majority of the cases.

Just in case there is a confusion: there is a difference between available sequences (~300 million in standard protein sequence repositories) and structures (~170k structures in th…

I respectfully disagree. AlphaFold 2 demonstrated almost perfect performance for a multitude of proteins for which no meaningful templates were available -- hence, it was not doing…

There is a growing trend to include Docker (or Singularity, which is more compatible with HPC architectures common in bioinformatics) images alongside codes. In particular, AlphaFo…