Viewing profile — chrisprobert

insitro | Machine Learning for Drug Discovery | South San Francisco, CA | Full Time | Onsite insitro is reinventing drug discovery by bringing cutting-edge machine learning in a cl…

I'm curious whether this is backed by Google File System ( https://static.googleusercontent.com/media/research.google.c... ), or something else.

What's interesting about this approach (TIL expansion) relative to other leading cellular immunotherapy approaches (CAR-T/NK and TCR) is that it doesn't rely on gene editing. Long …

Coupa Cafe on Ramona St. in Palo Alto, or the one in Y2E2 at Stanford.

Totally agree!

Announcing TensorFlow's new development roadmap mandate: copy everything PyTorch is doing :-)

Great to see this coming from a team with such a solid AI background!

Problem: Modern genomics is a commoditized science. Technologies like low-cost DNA sequencing, CRISPR DNA editing, and microarrays mean progress is happening too fast. Solution: Br…

I would put > 50/50 odds on there being a human alive today with at least one CRISPR-edited germline variant. I think the question is now how can we regulate/control CRISPR germlin…

Key question for digital health / biotech startups is whether direct to consumer (D2C) advertising for testing services (e.g. genetic carrier screening; cancer risk screening) woul…

Correct - their current v4 chip covers ~602K SNPs and they have > 1 M customers, so you couldn't uniquely identify all of them by genotype. But given the frequency of rare variatio…

You're right that Ancestry.com is focused on mtDNA, but 23andMe actually uses a custom Illumina microarray with autosome, allosome, and mitochondrial targets. Here's a study where …

Totally agree here - would be easy to fabricate DNA oligos with given mtDNA or STR sequences, especially if you know forensic investigators are only going to use very small target …

Good question. This problem affects multiple steps of a NGS-based forensics product: sample collection, DNA extraction, library preparation, the sequencing itself, alignment/assemb…

This article brings up problems with current PCR-based STR genotyping methods, but lacks information about technologies that are competing to be the future of forensic genotyping. …

I also enjoyed his post on the "Two Cultures of Computing": http://pgbovine.net/two-cultures-of-computing.htm Definitely something worth thinking about as we build tools for other …