Viewing profile — cassowary37

ELIZA wasn't the only chatbot in the late 1960s... this JAMA+AI podcast explores how their creators took very different paths in beliefs about AI in medicine

Not to take anything away from the meta-analysis and the important points in the blog post, but there's a glaring error in the abstract: "the weighted average effect sizes were as …

sorry, intended to elaborate: When I query my health system's deidentified research patient data registry, there are multiple individuals with both a diagnosis of schizophrenia and…

Just queried my health system database and this statement as it pertains to congenital cortical blindness is factually incorrect.

>"I feel like perpetuating this mindset is the ultimate sin of modern psychiatry and the entire industry of psychiatric pharmaceuticals" Hmm. Modern psychiatry is usually accused o…

Ironic that folks who work in CNS drug discovery spend much of their time worrying about how to get our molecules /into/ the brain... and less energy thinking about keeping non-CNS…

the studies (which admittedly are short-term) reflect remission - i.e., resolution of symptoms. This is a critical point: the goal is resolution of symptoms, not partial improvemen…

and HN refusal to pay attention to data when it relates to depression in 3..2..1... https://www.ncbi.nlm.nih.gov/pubmed/29477251 for moderate to severe depression, the kind most po…

actually that statement is itself rather presumptuous. How would you know that those of us who repeat it don't know? I can state with authority that may of us do.

A colleague of mine calls suicide 'a permanent solution to a temporary problem' - not to diminish it, but to recognize that for most people the desire to die is a temporary state. …

"Obscure Newspaper Discovers 40-year-old Concept Widely Used in Medical Literature" The concept of QALY goes back to 1976[0] and is a mainstay of cost-effectiveness literature. Fai…

Fun lithium fact: while most people start the lithium story with Cade (indeed, there's a form of lithium-responsive bipolar disorder which was sometimes called Cade's disease), it …

please be careful in equating the two: there are decades of studies, including large trials, demonstrating benefit for lithium. It's considered gold standard treatment for bipolar …

Here's my use case: as a scientist, I'm often in the position of needing to review multiple 20+ page grants or manuscripts, resulting in hundreds of pages at a time. I find it far …

I'd be curious to hear you define biologically valid. The heritability (variance explained by inherited features) for those diagnoses ranges from 0.3-0.8 - greater than many other …

Before everyone goes bananas citing Goodhart's law: many universities and academic medical centers in the US don't care at all about impact factor - they care about grant $$, perio…

For everyone complaining about peer review, another alternative to open review is paid reviewers who focus on a particular topic. For example, I'm an editor at a journal where stat…

Those are all very real problems (and as you point out, they impact grant review as well). On the other hand, fully transparent peer review doesn't necessary address most of them. …

nope (re being sure their ability to handle health benefits has improved)... just used them for a startup and their response to questions about integration with health benefits was…

Psychiatrist here... bravo. The feature creep, lack of rigor, and overtly commercial nature of most CBT lite apps is precisely the reason I've been reluctant to encourage their use…