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bglazer

HN member
Joined
Thu, Sep 26, 2013, 9:32 PM UTC
HN karma
3,258
Public activity
691 items

About bglazer

I'm Bryan Glazer. I'm a computational biologist studying complex biological networks and how to use machine learning to infer and perturb them to cure cancer and rare disease

Recent public activity

  1. comment
    Comment #49127408

    Yeah I'm begging these authors to at least *read* the LLM generated README's. They're so, so incomprehensible because the LLM has a super limited theory of mind for readers. They a…

  2. comment
    Comment #49010290

    Yes this is on the 777x, which is in pre-production and flight testing, seeking approvals from the FAA

  3. comment
    Comment #48872089

    > If we go in and just check the DNA for Downs or Parkinson's You should consider reading the wikipedia page about Parkinson’s disease.

  4. comment
    Comment #48834778

    Yes exactly, there are good and bad things to spend money on. This is a bad way to spend money for the reasons I explained above.

  5. comment
    Comment #48834526

    He's hubristic and selfish. None of his "research" is going to benefit anyone (himself included), making this essentially a huge waste of time and resources. Bryan will die just li…

  6. comment
    Comment #48518040

    You’re probably thinking about non-small cell lung cancers. Small cell lung cancer (SCLC) is still absolutely devastating. The most progress made on SCLC has just been getting peop…

  7. comment
    Comment #48286223

    Gene names aren't really acronyms in the traditional sense. Often they were originally conceived as acronyms at the time of the gene's discovery and naming, but the original acrony…

  8. comment
    Comment #48257495

    The whole article is just that someone got a spam political text about the Texas Senate GOP primary.

  9. comment
    Comment #48125120

    This is demonstrably untrue. IQ has increased consistently for decades, far faster than genetic factors can explain. Environmental factors like education, nutrition, and medical ca…

  10. comment
    Comment #48025127

    Yeah I have been reading a lot of posts like this lately. Technical blog post clearly written by an LLM summarizing something vibe-coded. They always start using project-specific j…

  11. story
  12. comment
    Comment #47916525

    Ah causal data! It’s a shame none of the scientists or statisticians thought of getting causal data. How would we get that? Well maybe we could just inject amyloid into a person’s …

  13. comment
    Comment #47679815

    This is insane, I love it.

  14. comment
    Comment #47558452

    I work in this field. It’s more or less correct but kind of lacking in detail. Cancer is a property of all multicellular life. I think it’s best understood as the behavior of a dyn…

  15. comment
    Comment #47253348

    This is quite similar to how eLife does publishing. You still have to submit to them but they basically just add reviewer comments and an “eLife Assessment” that serves as the qual…

  16. comment
    Comment #47249225

    > If you're an influential figure at a top-5 department in your field ... you all hate $journal. That's the problem, they don't hate these journals, they love them. Generally speak…

  17. comment
    Comment #47176184

    I think we could understand consciousness perfectly and still find it divine. In fact, I think however it arises is probably so beautiful that it would be wrong not to call it divi…

  18. comment
    Comment #47076689

    We absolutely do know about the molecular pathways that cause smoking induced lung cancer. It’s TP53 and RB1 mutations (among many others). There are probably more than a hundred t…

  19. comment
    Comment #47062743

    > a certain age range your eyes determine they've grown to the correct size based on how well they focus A certain age -> which one? Why? your eyes determine -> How? What molecular…

  20. comment
    Comment #47056656

    That's a lovely theory, if quite imprecise in terms of the actual biology of eye development. The actually important part of science (the part that requires a lot of expertise and …

  21. comment
    Comment #47054309

    Why does focusing on nearer things cause myopia? See if you're curious at even a basic level, you'd realize that there are important *details* about stuff like this where it actual…

  22. comment
    Comment #47039760

    I occasionally say please and thank you to ChatGPT for my own sake, not for the LLM's. They're sufficiently similar to humans that allowing myself to be a jerk subtly degrades myse…

  23. comment
    Comment #46451261

    Where were you doing this? Were you ever successful? How did you do it, like what were your tactics? So many questions! I’ve never heard about modern people doing serious persisten…

  24. comment
    Comment #46398787

    I genuinely did not expect to see a robot handling clothing like this within the next ten years at least. Insanely impressive I do find it interesting that they state that each tas…

  25. comment
    Comment #46295329

    This is a very tiring criticism. Yes, this is true. But, it's an implementation detail (tokenization) that has very little bearing on the practical utility of these tools. How ofte…