Viewing profile — benmaraschino

You (and others) may enjoy going down the rabbit hole of universality. Terence Tao has a nice survey article on this which might be a good place to start: https://direct.mit.edu/da…

They did. Check out Figure 2 in the paper.

They used a crossover design, so each subject served as their own control. Not a bad choice for trials like this as you gain a lot of statistical power with fewer participants than…

This book isn’t specifically about how to best support a blind child, but it might still be of interest. https://en.wikipedia.org/wiki/Far_from_the_Tree Either way, I hope for noth…

Counterpoint: the investigators used a crossover design, where each participant acts as their own control. Since within-subject variation Sample size is only a very small part of t…

Yes, this is a part of the problem. This is also why it’s hard to interpret the results of studies like this. Without knowing more about the methodology, it’s possible that a lot o…

There are payment models like this in use already. Look into capitation and accountable care organizations.

The causation arguably goes in the other direction too. You can't make money if you're unhealthy at baseline. Nor can you as easily acquire more education or new skills.

Yup. We don't know the full details, and I don't want to speculate any more than I have to, but it needs to be pointed out that subdural/epidural hematomas caused by head injury ca…

Aside from the fact that this demonstration was limited to the semi-public atrium of the Hart Senate Office Building—historically, a location where many such demonstrations have be…

The issue with coatings and lubricants is that you’d need to use a nontrivial amount for them to be effective, and that means the patient is at risk of aspirating the substance. Th…

One of these "studies" is a 2-page Google Doc with no real data. Another is the discredited Raoult study, which is under investigation by the journal [1]. Another study cited is al…

It’s nowhere near as difficult to make as the article may imply, though. Yes, that first-generation route is quite a doozy, involving some harsh conditions (multiple steps at -78° …

Unfortunately, this is a really bad analysis, because, for one, the author assumes in his model that the total number of infections won't change as the result of greater social dis…

You the nail right on the head. Especially regarding VALI. Personally, I’d also be worried about any residues in the system (e.g. lubricants, grease, etc.) being blown into your lu…

> Owning in a high cost of living geographic area is not a right, it is a luxury obtained mostly by luck This is kind of a weird take. Whether someone can afford to fulfill as basi…

Likely there would be little to no difference, because as it turns out, outcome risk is an awful predictor of benefit, especially among high-risk patients. Many high-risk patients …

It’s not practical. Patients on ECMO require anticoagulation, as do patients on cardiopulmonary bypass. This is a problem common to all systems which expose blood to foreign surfac…

Agreed. The point of criticism that the authors didn’t include all relevant models is among the lowest of the low-hanging fruit I can imagine one picking. And while the process of …

Exhibit A: Vimovo. One pill, consisting of two drugs that have been around for decades, and are available over the counter at any pharmacy. If bought separately, a month’s supply o…

The way many clinical research groups are structured (unfortunately) precludes code review, and to some extent, version control. Often for projects like the one referenced in the O…

Not the OP, but I work on similar problems, albeit in a different setting (healthcare, millions+ of patients). The gist is that you have to bake experimental design into the deploy…

No way. It's not even close. And I say this as a PhD candidate in one of these fields at Stanford. Grad school is what you make of it, to a large extent. There's definitely toxicit…

Well, at the end of the day, you can never really be sure of strongly ignorable treatment assignment/unconfoundedness, no matter what problem you’re working on. Especially if you’r…