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antichronology

HN member
Joined
Sun, Aug 27, 2017, 12:08 PM UTC
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Public activity
28 items

About antichronology

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Recent public activity

  1. comment
    Comment #44992244

    This is really interesting - I'm going to be honest I'm not an immunologist so this is my (LLM assisted) understanding of your comment: The immune system recognizes a sugar as a PA…

  2. comment
    Comment #44992147

    > finding sequences on NIH Almost! Yes most of the data is on NIH sub-institutes. For us we take most of the data from NCBI and intelligently pair it together. The training objecti…

  3. comment
    Comment #44992055

    That would be really cool. Navigating SRA and mining out reasonable $ relevant tasks is a huge bottleneck. I find it takes a large amount of effort to parse what the authors are do…

  4. comment
    Comment #44990471

    Here is the link for benchmarks and their utility: https://youtu.be/JdT78t1Offo?t=1444 "We have internal benchmarks. Yeah. But we don't we don't publish them." "we have internal be…

  5. comment
    Comment #44990396

    Thanks for engaging. Do you mind elaborating on your stance? From where we sit - there are people with diseases and mRNA is an effective way to revert them to a healthy state. I'd …

  6. comment
    Comment #44990390

    I watched an interview with one of the co-founders of Anthropic where his point is that although benchmarks saturate they're still an important signal for model development. We thi…

  7. comment
    Comment #44990032

    Huge fan of the work! I'm a big fan of papers from Seelig lab :)

  8. comment
    Comment #44989545

    We haven't looked into this deeply yet sounds interesting. Do you have any resources where to start looking at this? Feel free to reach out to us founders@blankbio.com

  9. comment
    Comment #44989533

    We think that Orthrus can be applied in a bunch of ways to non-coding and coding RNA sequences but it's definitely fair we're a bit more focused on RNA sequences currently instead …

  10. comment
    Comment #44989488

    This is a really interesting direction. There is this big field of Cell Free (cfRNA) cancer detection. We talked to a few people in the field and think that embedding sequences for…

  11. comment
    Comment #44988293

    > ground truth Hey yes, the ground truth for our evaluations is measured experimental data. Our models are benchmarked using mRNABench, which aggregates results from high-throughpu…

  12. comment
    Comment #44987806

    There is a number of different technologies. Some of the big ones are: - mRNA therapies: These therapies deliver a synthetically created messenger RNA (mRNA) molecule, typically pr…

  13. story
    Launch HN: BlankBio (YC S25) – Making RNA Programmable

    Hey HN, we're Phil, Ian and Jonny, and we're building BlankBio ( https://blank.bio ). We're training RNA foundation models to power a computational toolkit for therapeutics. The fi…

  14. comment
    Comment #34897546

    I think the apt comparison here is landing on the moon. Although overtly it carries little value, the technologies developed along the way are very valuable. As the article mention…

  15. comment
    Comment #34821373

    There is a great novel on a related topic: Permutation city by Greg Egan. The concept is similar where the protagonist loads his consciousness to the digital world. There are a lot…

  16. comment
    Comment #31035885

    Science Twitter is a really powerful tool for learning about new papers and being able to discuss with authors directly

  17. story
  18. comment
    Comment #21615228

    Where is the proof that human "rational" thinking is anything but curve fitting? I'm not convinced

  19. story
  20. comment
    Comment #18905371

    One of the top scientists of 2018 compiled by Nature was Jess Wade[0]. Her achievement is contribution to wikipedia specifically highlighting contributions of women and POC. When 9…

  21. comment
    Comment #18418288

    google maps has a lot of ratings and I find is good at suggesting a list of places from which I can select one. Look into the explore around me feature

  22. comment
    Comment #16485719

    Its possible that its better to leave the option more inaccessible to further incentivize yourself from reverting back to color mode. Maybe those few extra steps of converting back…

  23. comment
    Comment #16485631

    Has anyone tried changing their computer display to grayscale as well? I tried it for a bit but found that code syntax lacks color. Also graphics in papers all of a sudden are infi…

  24. comment
    Comment #16485607

    I'm wondering if personally keeping track of it somehow skews the statistics. Maybe the change is significant but overall not that big something like ~10% I would be interested in …

  25. comment