Viewing profile — antichronology
antichronology
HN member- Joined
- Sun, Aug 27, 2017, 12:08 PM UTC
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About antichronology
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Recent public activity
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Comment #44992244
This is really interesting - I'm going to be honest I'm not an immunologist so this is my (LLM assisted) understanding of your comment: The immune system recognizes a sugar as a PA…
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Comment #44992147
> finding sequences on NIH Almost! Yes most of the data is on NIH sub-institutes. For us we take most of the data from NCBI and intelligently pair it together. The training objecti…
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Comment #44992055
That would be really cool. Navigating SRA and mining out reasonable $ relevant tasks is a huge bottleneck. I find it takes a large amount of effort to parse what the authors are do…
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Comment #44990471
Here is the link for benchmarks and their utility: https://youtu.be/JdT78t1Offo?t=1444 "We have internal benchmarks. Yeah. But we don't we don't publish them." "we have internal be…
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Comment #44990396
Thanks for engaging. Do you mind elaborating on your stance? From where we sit - there are people with diseases and mRNA is an effective way to revert them to a healthy state. I'd …
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Comment #44990390
I watched an interview with one of the co-founders of Anthropic where his point is that although benchmarks saturate they're still an important signal for model development. We thi…
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Comment #44990032
Huge fan of the work! I'm a big fan of papers from Seelig lab :)
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Comment #44989545
We haven't looked into this deeply yet sounds interesting. Do you have any resources where to start looking at this? Feel free to reach out to us founders@blankbio.com
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Comment #44989533
We think that Orthrus can be applied in a bunch of ways to non-coding and coding RNA sequences but it's definitely fair we're a bit more focused on RNA sequences currently instead …
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Comment #44989488
This is a really interesting direction. There is this big field of Cell Free (cfRNA) cancer detection. We talked to a few people in the field and think that embedding sequences for…
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Comment #44988293
> ground truth Hey yes, the ground truth for our evaluations is measured experimental data. Our models are benchmarked using mRNABench, which aggregates results from high-throughpu…
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Comment #44987806
There is a number of different technologies. Some of the big ones are: - mRNA therapies: These therapies deliver a synthetically created messenger RNA (mRNA) molecule, typically pr…
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Launch HN: BlankBio (YC S25) – Making RNA Programmable
Hey HN, we're Phil, Ian and Jonny, and we're building BlankBio ( https://blank.bio ). We're training RNA foundation models to power a computational toolkit for therapeutics. The fi…
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Comment #34897546
I think the apt comparison here is landing on the moon. Although overtly it carries little value, the technologies developed along the way are very valuable. As the article mention…
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Comment #34821373
There is a great novel on a related topic: Permutation city by Greg Egan. The concept is similar where the protagonist loads his consciousness to the digital world. There are a lot…
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Comment #31035885
Science Twitter is a really powerful tool for learning about new papers and being able to discuss with authors directly
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Comment #21615228
Where is the proof that human "rational" thinking is anything but curve fitting? I'm not convinced
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Comment #18905371
One of the top scientists of 2018 compiled by Nature was Jess Wade[0]. Her achievement is contribution to wikipedia specifically highlighting contributions of women and POC. When 9…
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Comment #18418288
google maps has a lot of ratings and I find is good at suggesting a list of places from which I can select one. Look into the explore around me feature
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Comment #16485719
Its possible that its better to leave the option more inaccessible to further incentivize yourself from reverting back to color mode. Maybe those few extra steps of converting back…
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Comment #16485631
Has anyone tried changing their computer display to grayscale as well? I tried it for a bit but found that code syntax lacks color. Also graphics in papers all of a sudden are infi…
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Comment #16485607
I'm wondering if personally keeping track of it somehow skews the statistics. Maybe the change is significant but overall not that big something like ~10% I would be interested in …
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