Viewing profile — aBioGuy

Another anecdote (where it came from I do not remember) stuck in my brain was that Watterson's editor called him one day to tell him that STEVEN SPIELBERG was on the phone to talk …

In the title "....in the APP/PS1 Mouse Model of Alzheimer’s Disease" Given the decades of emphasis on clearing / preventing amyloids I would be fairly jaded. If someone (biotech) w…

The M4 MacBook Air (16gb, 1TB) retailed for $1400 ( https://www.bhphotovideo.com/c/product/1884084-REG/apple_mba... ). The M5 equivalent is now $1300. 1TB requires the CPU upgrade.…

I would like to point out (as I have seen this confused by many non-scientists) that the NIH (National Library of Medicine) provides a service called "PubMed" which collates peer-r…

Vehicular gas infrastructure is near 100 years of development and still has some edge cases. EV charging infrastructure is at about 10 years.

Well a Tern GSD has a max carry weight of 379 lbs and a max speed of 20 mph. Only needs a 0.5 kWh battery too. Has infinite range, depending on your fitness.

No has mentioned that the initial assertion is incorrect? The US Government sent troops to remove native inhabitants. Then they gave the land away. Having an army clear the land ah…

I remember when I moved to DC many years ago we drove to an art exhibit (in an empty building way away from the metro). There was a guy walking up and down the road saying "$5 to p…

Unpopular (?) opinion: don't worry about theft. If you are making developer-money then a $1000-$3000 bike is a trivial amount of money. Just use a cafe-lock with a sturdy chain and…

The cheapest and simplest strategy is to buy several external drives and leave them at work / someone else's house.

I thought that held the coaster AOL sent everyone in the mail.

Depending on where you live, you can cargo bike with your kids. If you check out the cargo bike forums there are always posts on how to attach baby seats to a bakfiets and such. I'…

Furthermore, scientific computing often (usually?) involves trainees. It can difficult to train people when small mistakes can have five figure bills.

If you make it pleasant to ride a bike - people will do it. Where I live, there is an off-street bike path that was completed about 10 years ago. Since then many new businesses hav…

The e-bike (pre COVID) would do about 2-3 24 mile trips a week. Plus the local trips. The other 1-2 days were a regular bike. That's a lot of rush hour miles removed from the road.…

Well the car has about 1000 miles in the same time frame. A second (non electric) bike has about 1500 miles. More importantly I was seriously considering replacing the car (it is q…

Tern GSD

I have two little kids. I also own an electric cargo bike. It has replaced over 2,000 car miles in the past year. I can bike to the grocery store, with two kids, and come back with…

Doesn't this suggest that cities should continue to build out their bike infrastructure? You can't get high bike use without protected lanes / etc.

It's popular with scientists (genomics) for making web portals to interactively share data / plots / analyses. The number of users to such sites is (often) measured in dozens of pe…

After I requested work buy me a tricked out MacBook (which I received literally last week), I saw the rumors that Apple would soon update their MacBook line. I was mentally prepari…

This is a nice intro. For a good collection of "worked out" "pipelines" to analyze different kinds of genomic data types (RNA-seq, ChIP-seq) in the R environment (the concepts are …

Yeah, that's why we subscribe. Digitally renting a movie is crazy stupid for busy parents of young children. It takes us 2-3 days to watch a movie (in the ~40 minute chunks we have…

This was published yesterday (title says 2012).

A 'gene' is a distinct set of DNA nucleotides. What changed were 7% of his gene's expression levels, across time. Which is not a particularly remarkable finding. If approximately t…