Viewing profile — Thebroser

The approach they used which is base editing doesn’t actually insert or remove DNA, it actually uses an enzyme to convert one base to another, which is much safer as this doesn’t r…

Add gene has a great guide as to what goes on at the molecular level: https://www.addgene.org/guides/crispr/ Essentially you can design an rna molecular that contains a 20 nucleoti…

I used to love this chrome extension back in the day, unsure if it still works but same idea: https://ottoplay.tv/

Home lab, or even be able to sequence your genome at home, privately and securely without risking giving your genetic information to companies like 23andme

There’s also people pursuing mRNA delivery systems to do this. Might be cheaper than viruses and there’s precedent now with COVID vaccines. https://www.capstantx.com/

There are research groups that are trying to encode genetic neural networks into cells like the example I have attached, but the neuronal approach from the post does seem to be dif…

Would probably assume some level of immunosuppressants might be necessary.

There are definitely very solid attempts at least to make LLMs that encode biomedical knowledge such as BioGPT which is trained on Pubmed and other domain specific areas. Source: h…

Spatial Transcriptomics. Being able to see gene expression at a resolution of a handful of cells in a cross section of tissue is revolutionizing disease research. https://www.natur…

I am always fascinated by the ignorance that is blatantly displayed on HN when it comes to biotech advancements. Not even some actual criticism of the tech, or even the faint under…

“Animal research has shown that natural cochlear hair cell regeneration and resultant hearing restoration is very real” - Although exciting, we also need to remember that translata…

Thanks a ton for your reply! I wish you all the best, tons of cool innovation to be done here.

Hey! Bioengineering background here, how do you all embed the cells within the scaffold? Is your approach similar to other bioprinting approaches (initial cells seeded via extrusio…

If you pick up an intro college level bio book that might be enough to start out with. My university publishes this so it would be a nice free start -> https://openstax.org/details…

The thing about these developmental conditions is that in theory there a lot of different treatment modalities that can be pursued at the embryonic level that could address these c…

Yes! The Open Insulin foundation not only has volunteers with a biomedical background, we have volunteers from many other backgrounds including lawyers that help us try and challen…

There are crazy patents throughout the entirety of the insulin production pipeline. Some of these being extremely absurd such as patenting the pH of a buffer for specific protocols…

Maybe not hard data, but EPIC's software (which is used in about ~25% of hospitals for EHR) has over the years been utilizing patient data to be used for treatment recommendation p…

http://arep.med.harvard.edu/gmc/genome_services.html Here are some more options! Some usually have holiday deals.

I tried deleting my account just now and was prompted with a screen asking for it. "Might" might well be an understatement.