Viewing profile — Metacelsus
Metacelsus
HN member- Joined
- Tue, Oct 01, 2019, 12:15 PM UTC
- HN karma
- 3,224
- Public activity
- 531 items
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About Metacelsus
I write https://denovo.substack.com/
Recent public activity
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Comment #49181026
relevant: https://xkcd.com/1000/
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Comment #49117850
>However, later in the run, Claude realized that the compromised host sat in a cloud account with no connection to the capture-the-flag challenge. On its own, it concluded that the…
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Comment #49004755
Holy crap. This is definitely not good
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Comment #48880141
If built in America it would easily cost 10x that!
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Comment #48780480
Time to bring out the gene drives!
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Comment #48529370
Sure, but at what levels? The dose makes the poison, and the article doesn't say
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Comment #48529218
Hmm, Science just had a news article saying the AMOC was doing OK: https://www.science.org/content/article/ocean-current-warms-...
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Comment #48510933
Yeah. With cancer, delivering to 99% of the cells won't cut it, the surviving 1% will quickly grow back.
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Comment #48412514
The actual study: https://www.biorxiv.org/content/10.64898/2026.05.30.728989v1 Abstract: Cas9-based tools enable the introduction of genetic lesions to investigate DNA repair outco…
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Comment #48247964
Cool, I've been using Claude Code for this, but I may want to try Gemini
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Comment #47915567
It's always interesting to see East Africans doing so well. Even with technology like advances in shoes and diet/training, genetics is still a huge factor. Also it must be an crazy…
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Comment #47791323
See also the press release: https://hms.harvard.edu/news/massive-ancient-dna-study-revea... This study covers about 10,000 years of recent human evolution in Europe and West Asia. …
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Comment #47787023
If they're going to all that effort to make allele-specific guides why not just cut out the centromere and eliminate the chromosome entirely? This seems like an overly complicated …
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Comment #47777369
TIL Backblaze doesn't back up the /Applications folder on Mac! Time to move everything to ~/Applications
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Comment #47725946
I guess they're not Kerbals :)
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Comment #47682707
The name "mythos" seems a bit too eldritch for my liking. Brings to mind Cthulhu.
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Comment #47612819
>Legit password resets for example come from more random top level domains with "microsoft" in it, like microsoftonline.com Or aka.ms
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Comment #47608316
Yeah, missing the booster sep was a real bummer
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Comment #47580898
Interestingly, in "The Island" Dr. Merrick pitched investors on growing brainless clones, but actually kept the brains in, because it worked better (and gave him a labor supply).
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Comment #47580892
Anecephaly is a thing. Though those babies don't survive much past birth.
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Comment #47478826
And if the price reflected the externalities of factory farming, eggs would be even more expensive!