Live data from Hacker News

Viewing profile — Metacelsus

Metacelsus

HN member
Joined
Tue, Oct 01, 2019, 12:15 PM UTC
HN karma
3,224
Public activity
531 items

About Metacelsus

Grad student working on in vitro oogenesis.

I write https://denovo.substack.com/

Recent public activity

  1. comment
    Comment #49181026

    relevant: https://xkcd.com/1000/

  2. comment
    Comment #49117850

    >However, later in the run, Claude realized that the compromised host sat in a cloud account with no connection to the capture-the-flag challenge. On its own, it concluded that the…

  3. comment
    Comment #49004755

    Holy crap. This is definitely not good

  4. comment
    Comment #48880141

    If built in America it would easily cost 10x that!

  5. comment
    Comment #48780480

    Time to bring out the gene drives!

  6. comment
    Comment #48529370

    Sure, but at what levels? The dose makes the poison, and the article doesn't say

  7. comment
    Comment #48529218

    Hmm, Science just had a news article saying the AMOC was doing OK: https://www.science.org/content/article/ocean-current-warms-...

  8. comment
    Comment #48510933

    Yeah. With cancer, delivering to 99% of the cells won't cut it, the surviving 1% will quickly grow back.

  9. comment
    Comment #48412514

    The actual study: https://www.biorxiv.org/content/10.64898/2026.05.30.728989v1 Abstract: Cas9-based tools enable the introduction of genetic lesions to investigate DNA repair outco…

  10. story
  11. comment
    Comment #48247964

    Cool, I've been using Claude Code for this, but I may want to try Gemini

  12. story
  13. comment
    Comment #47915567

    It's always interesting to see East Africans doing so well. Even with technology like advances in shoes and diet/training, genetics is still a huge factor. Also it must be an crazy…

  14. comment
    Comment #47791323

    See also the press release: https://hms.harvard.edu/news/massive-ancient-dna-study-revea... This study covers about 10,000 years of recent human evolution in Europe and West Asia. …

  15. story
  16. comment
    Comment #47787023

    If they're going to all that effort to make allele-specific guides why not just cut out the centromere and eliminate the chromosome entirely? This seems like an overly complicated …

  17. comment
    Comment #47777369

    TIL Backblaze doesn't back up the /Applications folder on Mac! Time to move everything to ~/Applications

  18. comment
    Comment #47725946

    I guess they're not Kerbals :)

  19. comment
    Comment #47682707

    The name "mythos" seems a bit too eldritch for my liking. Brings to mind Cthulhu.

  20. comment
    Comment #47612819

    >Legit password resets for example come from more random top level domains with "microsoft" in it, like microsoftonline.com Or aka.ms

  21. comment
    Comment #47608316

    Yeah, missing the booster sep was a real bummer

  22. story
  23. comment
    Comment #47580898

    Interestingly, in "The Island" Dr. Merrick pitched investors on growing brainless clones, but actually kept the brains in, because it worked better (and gave him a labor supply).

  24. comment
    Comment #47580892

    Anecephaly is a thing. Though those babies don't survive much past birth.

  25. comment
    Comment #47478826

    And if the price reflected the externalities of factory farming, eggs would be even more expensive!