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Why not just use a dictionary, or why not just leave the type unannotated? If you really can't (or don't want to) say anything about the type, then don't. Python is dynamically typ…

Have you tried this yet? Looks like it uses the ms graph API https://github.com/jgunthorpe/cloud_mdir_sync

I turned this on and for most "general" use cases I found it useful, I also observed a downward biased in a family of "quantatitative estimation" tasks, so just remember when you h…

It’s kind of wild how much work really smart people will do to get python to act like Fortran. This is why R is such a great language IMO. Get your data read and arrays in order in…

The comment you linked is a response to my comment where I tried (and failed) to articulate the world in which R is situated. I finally "RTFA" and the benchmark I think perfectly d…

Every two weeks or so I peruse github looking for something like this and I have to say this looks really promising. In statistical genetics we make really big scatterplots called …

R was heavily inspired by scheme, and I think that's a big part of why it's so popular in the scientific community (it's a great language for authoring DSLs). In fact, DSLs are so …

This is what's so brilliant about the Microsoft "partnership". OpenAI gets the Microsoft enterprise legitimacy, meanwhile Microsoft can build interfaces on top of ChatGPT that they…

QR decomposition isn’t in BLAS, you’re probably thinking of LAPACK.

No. OTOF is the gene symbol. Referring to the gene as otoferlin is perfectly legitimate

That’s certainly not true in scientific computing. For us, dynamic is very much the exception rather than the rule.

How might one go about making the nuclear family a universal?

That’s absolutely not true about Microsoft. They’re very clear about how they use your data. If they’re mining data in secret against their own terms that’s felonious criminal beha…

I think what it comes down to is that it's very difficult to divorce modeling from inference.

It's absolutely not "on the way out". Lots of very slow moving, very deep pocketed organizations working on very long time horizons are heavily invested in HDF5. The same can't be …

Does pigz offer any advantages over bgzip?

I spend most of my time in the parallel universe that is scientific computing/HPC. In this alternate reality SQL (not to mention databases) never really took off. Instead of scalab…

How often do you have markup in the middle of a phrase you're searching for? It seems to me like if that's really important to you, then just don't use a lot of markup?

I've never seen a 15x difference in density between gzip and zstd on genomic data in an apples-to-apples comparison; I'd be really curious to learn more about how you achieved that…

These MPI-based scientific computing applications make up a bulk of the compute hours on hpc clusters, but there is a crazy long tail of scientists who have workloads that can’t (o…

Roaring bitmaps are compressed bitmaps and they're pretty great. https://roaringbitmap.org/about/

You have to understand that many R users don't have root access the the machines they're working on.

R packages on CRAN need to be able to install without internet connection so I'm skeptical that that's the case. CRAN packages also don't allow for dependency on R packages that ar…

I would argue that if "reasonably competent" means "gets in accidents less frequently and has fewer moving violations", the "idiot" in the minivan is very likely more competent tha…

I often feel like bioinformatics is like this steampunk alternate reality where, because HPC clusters don't generally do database administration, all the technology and the ecosyst…