Viewing profile — CipherThrowaway

It's easy to say "document what you can" when you leave "document", "what", and "can" loosely undefined. The article gives us a why and then leaves out the who, what, when, where a…

So where is the "case for documentation"? The author provides no vision and no actionable recommendations. Documentation is not even mentioned until the end of the article. Anyone …

If you had to give a percent figure, what do you believe your mother's chances were of discovering a radical curative treatment for SCC and curing her own cancer?

I notice you've watered down your terminology from "cure" to "improvement on clinical best practice" which are pretty different things in the context of cancer treatment. However, …

Exhausting all treatment options is not the same as having nothing to close. There's no shortage of cancer patients at end-of-life stage undergoing aggressive treatments and/or exp…

> This virologist did believe that her colleagues were sitting around not rolling out something that would cure her. And because her outcome was so unexpected and unusual it got pu…

The development of PD-L1 expression was also interesting.

What doesn't make its way into case studies and HN headlines is all the stories of people who did get access to uncertain treatments and died anyway. Sometimes faster than they wou…

This is a big simplification. 1. The interaction between oncolytic virotherapy and host immunity is complex. Consider that oncolytic viruses are also targeted by the immune system.…

> He's not wrong though. It's more of a "not even wrong" statement. It's the kind of useless and reductive analysis poor leaders trot out from a position of personal frustration af…

Moonshot or no, these incremental improvements in surgery do translate into cured patients and saved lives. Surgery is the initial intervention in many cancers and the course of di…

Dietary advice is one thing. Woo peddling and fringe medicine is another. The original question didn't even ask about rheumatoid arthritis. I'm not overreacting. There are many peo…

I know this is well-intentioned, but please keep this stuff out of health threads about serious health conditions. This kind of material lacks rigor, dramatically misrepresents the…

"AI assistants are bad" isn't the take. The thing making people feel icky/uncomfortable about Her - and about the 4o demos - is not the idea of Samantha but the idea of Theodore. I…

This is the thing that is so wild to me. Outside of tech, everyone I encounter in day-to-day life intuitively understands that tech dudes inventing AI voices to flirt with them is …

> but I don't think she has any rights to voices that merely sound like hers, when they're not being used to fraudently imply that she's involved. IANAL but it's actually not that …

There is no point to the article. It's another boring anti-React/Electron screed but with a conspiratorial, junior high polsci bent to it. Having frameworks that allow more devs to…

Quick check of the bio reveals his alternative is Svelte. Weird since the usual Svelte argument is that it's so simple anyone can pick it up and be effective the next day - unlike …

Feels a lot like a lengthier, polemical way of saying that frameworks become popular because they allow more people to do more stuff more easily. But this is bad because businesses…

If medicine is just following a decision tree why would we need LLMs to do it? Computers have been able to follow decision trees for 70 years or something.

> Most places I've worked in the last 6 or so years are obsessed with tooling and add so many lint rules that it's often impossible to merge your pull request if you decide to form…

I recovered, but it took a long time. I don't know about RA. OPs blog post sounds a bit too optimistic for someone living with untreated RA for 3 years.

Yeah, I agree. In some sense, tendons remodel more easily than the brain. Somatic pain disorders can easily ruin someone's life.

The question here isn't about damage but about what mechanisms in the "pain pathway" are responsible for OP's specific experience of this pain. One day he has sudden, debilitating …

Seems like a bizarre omission from the article given the number of tangents and topics covered. My guess is that going down the traditional medicine route lead to him being told th…