Viewing profile — AstroDogCatcher

Yes. First experienced TMJ pain as a teenager and almost overdosed on painkillers while trying to get rid of it at 3AM. Still recurrs about 2-3 times per year, but I've now learned…

Thanks - fascinating stuff. I'm now even more convinced I want to give it a try, but I think I'll play around with public data and tutorials before leaping into home sequencing.

Interested outsider here; I work with a lot of HCLS research customers but don't have a biology-related background. Can you explain the problems with the Nanopore sequencer accurac…

Exactly the same situation in the UK - snow is common but rarely persistent enough to justify the infrastructure investment to deal with it. Also, having an excuse to combine moani…

As a recent Mac adopter after spending 10 years as a Linux user, Homebrew is exactly what I need it to be. Linux OS package managers are, almost by necessity, full of outdated pack…

In a cloud setting, I guess having user /home dirs on separate volumes from the root disk and having them relocatable is a reasonable analogue. The real issue is that much like the…

The key difference is that one of these things has the backing and approval of recognized governments who also control law enforcement, while the other is just some guys on the int…

Suggesting the explanation provided is insufficiently clear, no?

Julia has some nice ideas but it is time for a do-over as a fully open language (ie without the commercial backer actively upselling in their mailing list), and with the "time to f…

The latter - the results are astoundingly bad. You should remove that demo ASAP.

I just tried the demo sketch thing on the Gradio site and it wasn't able to correctly interpret a single digit I tried, even after 6 or 7 attempts with different values. Serious qu…

At this point I think if you desperately need MS Office, MacOS is the way to go. I will never buy a Windows machine again, and being forced to use it in a work setting would be a d…

Perhaps we should put computers inside each businesses location, to minimize the blast radius of any specific outage and make people take responsibility for their own stack.

I am mildly opposed to technology advocacy actually, but that is besides the point. Dev advocates are paid to market software and tools, and everyone knows their inherent bias and …

I understood you perfectly; I simply don't agree. Your model for decision-making bears no resemblance to reality at Amazon or anywhere else.

This is nothing to do with one-way/two-way door decisions, you are conflating that concept with an understanding of "unintended consequences" in order to take a cheap shot at Amazo…

I am mostly indifferent to bitcoin and cryptocurrencies in general, but strongly opposed to people shilling for them. I see no evidence thus far for bitcoin being anything other th…

Bitcoin being legal tender in certain places seems like more of a negative indicator on those countries, rather than a positive indicator for bitcoin.

I'm a regular employee but at a professional services org - you basically described how I generate my timesheets. The main difference is that at the end of the day I try to just st…

For some customers, I imagine this will start off as an emotionally-driven request...until they see the price.

The Julia crowd really need to hang less value on the REPL - people writing serious production code don't use one, and scientists using Python have moved on to notebooks. At this p…

I'd flip that meme slightly; it is true that scientists write shitty code...but it turns out computer scientists do exactly the same, and with less humility.

100% agree. Getting an M1 Mac has solidified this feeling for me too; I still want to be a Linux desktop user on philosophical grounds and will never go back to Windows, but as I a…

Feels like this exists mostly as a prop for immature CS students to "impress" people with.

If compliance is an issue, I doubt whether there is such a thing as a "suitable substitute". Certainly none of the commercial applications I interact with accepted CentOS as an alt…