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It's certainly quite pleasant to work with...but I would rather use sql for etl, the backend be whatever it needs to be... The real world data transformations can get gnarly very q…

Well the onus is obviously on a driver to make sure they see what they need to see. And that they drive a vehicle that allows them to see things. That doesn't mean the pedestrians …

I looked it up and it's quite fascinating indeed but I cannot stop thinking about sanitary challenges...

I am not sure what specifically you mean by "AI" here but it's a bit naive (no offence) to think the field is so dumb that it haven't been looking at "AI" for a few years already. …

Thanks for the reply. I have read your post but I haven't seen the preprint obviously and without knowing the details I remain skeptical. > The WGS NICU diagnostic rate is only ~30…

The post is written almost as if there is no prior art on (germline) variant interpretation. In fact, it is an established niche field with multiple commercial vendors existing for…

These are not bankers, but the culture is still bonkers

You are asking about one-sided vs two-sided tests. Not really "more often" because formal type 1 error rate is still the same. I'd say two-sided tests leave more space for post-hoc…

Interesting. I am wondering why would anyone use a t-test when the experiment is clearly modelled by a binomial distribution: 250 independent questions and each one is either answe…

10k only??? Incomparable to the value delivered any way you measure it...

It's suddenly you who's deciding for others what's stupid?

Exponential productivity gains?;)

> Customers dictate what gets produced. Sure? It seems to me that the companies dictate what I consume. Many many times I wanted to buy exactly the same clothes item or shoes to re…

Why massive discounts seem to be much more of a thing in the US compared to Europe?

ra is autoimmune

If anything focus gets better without sugar and excessive carbs for me - but those work well for outdoors or workouty days I find.

Looks like it's true that low-carb adapted athletes rely more on fat oxidation during exercise but performance suffers nonetheless because of increased oxygen demands that basicall…

If your employer gets you a nvda card or openai subscription, it doesn't automatically mean you are getting richer, agreed? And the richness of life it's another philosophical disc…

Yoir choice between the red pill, the blue pill or no pill is pretty obvious but this choice is highly subjective.

Also pfizergate featuring von der leyen.

I'm with you on this. People who pathologize themselves or others - assuming they're malfunctioning rather than acknowledging they might simply be living a life that doesn't fit - …

> ... in professions where skill is essential and performance is both visible and attributable to a specific person, particularly in fields such ... fund asset management ... Laugh…

How is it unstable? It's one of the most reliable pieces of software I have used honestly. In any case 'nix-shell -p erlang|elixir' does not seem too complicated to me.

Well Nix is the only sane way I know to manage fully reproducible envs that incorporate programs/scripts spanning multiple ecosystems. Very common situation in applied data analysi…