Viewing profile — 100ideas

what a non-answer answer!

You just answered my question: Is it the case that UnitedHealth and Cigna each own (or control) one of the "big three" PBMs? If so, that is a just crazy - the control insurance pre…

Very interesting comments and moderation discussion on this article.

I think you both make valid points, but I also get the sense that the article is articulating insights gained from pure math explorations into the theoretical limitations of learni…

Oops, thanks. I changed it.

Basically, as LLMs scale up, the author (Soatto, VP at AWS) suggests they're beginning to resemble Solomonoff inference: hypothetically optimal but computationally infinite approac…

Yes, I should have made that clear in my first comment. Thanks for doing so. I used the quote in my title because I found it a fascinating way to start a technical blog post, and i…

I found the opening quote of this article to be intriguing, especially since it was from a 1992 research lab: “One year of research in neural networks is sufficient to believe in G…

Who are the lobbyists pushing this?

So the control was the previous GILEAD drug (presumably a weekly injection?) for the same condition (HIV+)?

reminds me of the anthropic's recent work on identifying the neuron sets that correlate to various semantic concepts in Claude: https://news.ycombinator.com/item?id=40429540 "Scali…

Ditto. The larger question is how does the linear sequence of DNA (primary sequence) ultimately drive the spatio-temporal development program that leads to mature differentiated ce…

one of my favorite books since high school. I remember mentioning it to my HS English teacher before class one day (20 years ago) and she amazed and surprised me by replying "oh th…

Dear god, how is that an advantage? Are we all here just rooting for techno-dictator supremacy?

This comment is tone-deaf to the unique (and effective? TBD) arrangement of the board OpenAI 501(c)3 without compensation and the company they regulate. Your comment strikes me as …

what's the deal with the host url?

In principle, these costs could be 1000x less. Much like minicomputer -> dell price shift.

VSI thermodynamics is my favorite so far, it covers statistical mechanics of gasses, Boltzmann distribution defn of temperature… if you don’t know what these concepts are, I am con…

The author referenced a paper from 2009 about the microRNAs and BK subunits: "Post-transcriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptat…

And here is the Nature article: "Hidden order across online extremist movements can be disrupted by nudging collective chemistry" https://www.nature.com/articles/s41598-021-89349-3…